| 1 | 15 March 1981 | Long Beach | United States Grand Prix West | Alan Jones | Williams | 80 | 1:50:41.33 |
| 2 | 29 March 1981 | Autódromo Internacional Nelson Piquet | Brazilian Grand Prix | Carlos Reutemann | Williams | 62 | 2:00:23.66 |
| 3 | 12 April 1981 | Autódromo Juan y Oscar Gálvez | Argentine Grand Prix | Nelson Piquet | Brabham | 53 | 1:34:32.74 |
| 4 | 03 May 1981 | Autodromo Enzo e Dino Ferrari | San Marino Grand Prix | Nelson Piquet | Brabham | 60 | 1:51:23.97 |
| 5 | 17 May 1981 | Zolder | Belgian Grand Prix | Carlos Reutemann | Williams | 54 | 1:16:31.61 |
| 6 | 31 May 1981 | Circuit de Monaco | Monaco Grand Prix | Gilles Villeneuve | Ferrari | 76 | 1:54:23.38 |
| 7 | 21 June 1981 | Jarama | Spanish Grand Prix | Gilles Villeneuve | Ferrari | 80 | 1:46:35.01 |
| 8 | 05 July 1981 | Dijon-Prenois | French Grand Prix | Alain Prost | Renault | 80 | 1:35:48.13 |
| 9 | 18 July 1981 | Silverstone Circuit | British Grand Prix | John Watson | McLaren | 68 | 1:26:54.80 |
| 10 | 02 August 1981 | Hockenheimring | German Grand Prix | Nelson Piquet | Brabham | 45 | 1:25:55.60 |
| 11 | 16 August 1981 | Red Bull Ring | Austrian Grand Prix | Jacques Laffite | Ligier | 53 | 1:27:36.47 |
| 12 | 30 August 1981 | Circuit Park Zandvoort | Dutch Grand Prix | Alain Prost | Renault | 72 | 1:40:22.43 |
| 13 | 13 September 1981 | Autodromo Nazionale di Monza | Italian Grand Prix | Alain Prost | Renault | 52 | 1:26:36.897 |
| 14 | 27 September 1981 | Circuit Gilles Villeneuve | Canadian Grand Prix | Jacques Laffite | Ligier | 63 | 2:01:25.20 |
| 15 | 17 October 1981 | Las Vegas Street Circuit | Caesars Palace Grand Prix | Alan Jones | Williams | 75 | 1:44:09.077 |
